- Many of these hybrids will be fighting for the villains' side, meaning the good guys' impending defeat during the Raid will partly come down to getting overwhelmed by the inherent power and advantages of DIVERSITY brought to the table by the multiracial troops in Kaido and Big Mom's armies. One big example is one I've mentioned several times already: Jack undergoing a slight transformation similar to Derringer to combine the strengths of his Fishmen ancestry with his Zoan might.
In order to combat this, we may just see the Strawhats and their allies having to resort to mixing up their own game ( so to speak ) as well by following suit in their unique ways: using others' weapons and items ( kinda like what Zoro did w/ Kamazo's sickle ), coming up with new techniques inspired by those of friends and crewmates, forming unique tag teams and combined attacks similar to what see on Thrillerbark, etc.
I've mentioned already ( forget if it was here or orojackson ) that I foresee the Strawhats in particular adopting new attacks and powerups based on that of their fellows, something I was expecting to occur later post-third-timeskip, but may be we'll see this play out in earnest during Wano.
For example, some have mentioned the possibility of Sanji possibly eating one of Chopper's rumble balls to potentially unlock whatever genetic enhancements Judge originally intended for him. Quite frankly, this is definitely something I could see occurring, at least as a one-time powerup; one which may lead to some disastrous results once the dust clears. In any case, Oda may finally hammer home the obligatory Kamen Rider salute by portraying Sanji NOMing a rumble ball to transform into some kind of Cricket Man ( my prediction for Judge's intended insect DNA grafts ).
But then, I also theorize that Sora managed to negate Judge's machinations -- at least in Sanji's case -- by adding genetic modifications based on that of an animal with DNA extremely similar to our own, ie a pig lol. So yeah, if we see the Sanji/Rumble Ball theory play out, expect Sanji to cycle through a series of wild transformations same as Chopper, one of which bearing a resemblance to a pig.
In Zoro's case, I've already stated that I foresee him losing one or more swords throughout the arc, so it's a fair bet he'll using more impromptu weapons, including those belonging to other characters ( kinda like a certain sword-thief he crossed paths with ). That he'll one day be swinging around a boat paddle oar same as a certain famous swords saint is a foregone conclusion. On that note, whatever weapon Zoro eventually ends up converting into a black "blade" will be composed of wood, mark my words....cuz spoiler alert: Mihawk's Yoru is in fact basically a wooden stake carved into the form of a cross-like sword, only turned black by his haki.
Nami - takes a cue from Robin and Shinobu; targets her male enemy's nuts wth Shinobu's men-sealing ninpo arts! More importantly, she'll later taken inspiration from Shinobu's ninja kite thingie to formulate plans for her own gliding mechanism....to be continued on that front.
In short, Nami adds some ninjitsu tricks to her repertoire.
Robin - goes back to her early grappling roots, but this time she takes a cue from Chopper and Franky in order to go the full pro wrestling route; that's right, we might see Robin straight up going close-quarters and personal by directly suplexing bitches....maybe even in fullbody-bloom giant form. Bigger they are and all that.
Also, it allows Oda another shout out to wrestling gag manga Kinnikuman if Robin were to say take another cue from Usopp and many others by adopting her own colorfully costumed alter-ego by the name of....Robin Mask.
https://kinnikuman.fandom.com/wiki/Robin_Mask
Robin's walls are gradually crumbling....tis only a matter of time.
Brook - follows Chopper, Luffy, and even Franky's example by adapting his own series of transformations to his repertoire, made possible by not just rearranging the bones of his skeleton but also "docking" bones belonging to other skeletons as well. I think Brook will most def gain the ability to "possess" things -- at the very least other bones in this case -- so it's only natural we'll see this spring forth during the battles in Wano, what with the blatant references to Brook being the giant skeleton yokai known as the Gashadokuro. Only after he unlocks this new ability he truly will gain a humongous size worthy of legend by assimilating other skeletons.
https://en.wikipedia.org/wiki/Gashadokuro
And given Brook's connection to whales, it only stands to reason we'll also see a reference to the skeletal cetacean yokai known as the Bakekujira as well, further increasing the odds of potential bone-assimilation/possession abilities.
Anyways, that's a few for now.